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1993 May;81(5 ( Pt 2)):819-23. Links Acute fatty liver of pregnancy in a patient with chronic active hepatitis and progesterone associated hepatocyte alpha 1-antitrypsin inclusions.Minton D, Yancey MK, Dolson DJ, Duff P.Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville.BACKGROUND: Acute fatty liver of pregnancy is a rare, potentially fatal condition that shares many of the signs and symptoms of severe preeclampsia. Early reports of this condition noted alarmingly high fetal and maternal mortality rates. However, recent reports have described more favorable outcomes due to prompt recognition and aggressive treatment. We here describe a progesterone patient progesterone with acute fatty liver of pregnancy superimposed on chronic active hepatitis. CASE: A 27-year-old woman, para 0-1-2-1, presented at 36 weeks' gestation with a 2-week history of malaise, nausea, emesis, diarrhea, and an 18-lb weight loss. The serum concentrations of transaminase enzymes, bilirubin, and alkaline phosphatase were increased, and a mild coagulopathy was present.
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