1982 Aug;9(2):157-62. Links Can hrt children’s
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1982 Aug;9(2):157-62. Links Can children’s tetracycline-induced fatty liver in pregnancy be attributed to children’s choline deficiency?Gwee MC.Pregnant women, especially those in their third trimester, are particularly susceptible to tetracycline-induced fatty liver. Experimental evidence obtained in rats suggest that the precipitous fall in children’s maternal liver choline concentration nearing the end of pregnancy could lead to a severe reduction in the lipotropic activity of the liver. It is hypothesised that the liver in this state will be at much greater risk of developing fatty degeneration, especially if it is exposed to hepatotoxic agents such as tetracycline.PMID:
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