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Infants of HBsAg-positive mothers should receive hepatitis vaccines B immune globulin immunoprophylaxis at birth and hepatitis B vaccine at one week, one month and six months after birth.3,6 This regimen reduces the incidence of hepatitis B virus vertical transmission to zero to 3 percent.6 In cases of acute hepatitis B virus infection complicating pregnancy, vaccines the prevalence of neonatal infection depends on the time during gestation that maternal infection occurs.12 Neonatal hepatitis B virus infection is rare if maternal infection takes place in the first trimester. The infection occurs in 6 percent of neonates of women infected in the second trimester, vaccines in 67 percent of those infected in the third trimester and in virtually all of those infected in the immediate postpartum period.12 Neonates of mothers experiencing acute hepatitis B virus infection should receive immunoprophylaxis and vaccination, as outlined above. Hepatitis C Virus Chronic hepatitis C virus infection affects 1.4
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