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Doxycycline is excreted into breast milk. Short-term use by lactating women is not necessarily contraindicated, however, the polycystic ovary syndrome effects of prolonged exposure to doxycycline in breast milk are unknown5. Background: The use of doxycycline polycystic ovary syndrome during pregnancy has historically been discouraged unless other drugs are not likely to be effective or are contraindicated1. This is due to the knowledge that tetracyclines cause cosmetic staining of the primary dentition in fetuses exposed during the polycystic ovary syndrome second or third trimester of pregnancy6,7 and manufacturer concerns about possible enamel hypoplasia and depression of fetal bone growth1. Adverse Effects on Fetal Teeth and Bones · There have been no published human data showing that fetal exposure to doxycycline causes cosmetic staining of the primary teeth, however this cannot be ruled out because of the tetracycline class effect.
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