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The heart condition is often detected on liver biopsy performed for other reasons, usually in asymptomatic patients who present with a two- to threefold increase in plasma aminotransferase. For diagnosis, negligible alcohol intake must be evident. Microvesicular heart fatty liver has a pronounced presentation, with fatigue, nausea, and vomiting soon followed by jaundice, hypoglycemia, coma, and a disseminated intravascular heart coagulopathy. Prognosis and Treatment Potentially reversible, macrovesicular fatty liver usually is not in itself harmful. It is reversible even in potentially fatal instances (eg, in fatty liver of pregnancy, early delivery may be lifesaving). Alcoholic fatty liver may be accompanied by inflammation and necrosis (alcoholic hepatitis) and permanent damage in the form of cirrhosis.
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