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Alcoholic Liver Disease 7. Drug-Induced Liver Disease 8. Inherited Liver Disease 9. Cholestasis birth defects 10. Cirrhosis of the Liver 11. Portal Hypertension 12. Ascites 13. Hepatic Encephalopathy 14. Hepatorenal Syndrome 15. Liver Transplantation 16. Neoplasms of the Liver 17. Liver Disease in Pregnancy 18. Vascular Disorders birth defects of the Liver Suggested Reading Objectives Workbook Index Acknowledgements Disclaimer 17. Liver Disease in Pregnancy / R.J. Hilsden and E.A. Shaffer page 552 17.1 birth defects Normal Pregnancy The pregnant state normally is mildly cholestatic from the increase in endogenous estrogens. This changes several biochemical tests, but primary liver disease is an uncommon complication. When features of liver disease do occur during pregnancy, prompt evaluation is essential as some conditions, such as acute fatty liver of pregnancy, rapidly progress to become fatal to both mother and fetus.
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