Presentation typically is in fatty acid definition acute fatty liver of pregnancy

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Presentation typically is in the third trimester acute fatty liver of pregnancy with the insidious onset of pruritus. In half of these patients, jaundice follows. Other cholestatic features include acute fatty liver of pregnancy dark urine and, occasionally, pale stool. Otherwise women generally feel well, without nausea, vomiting or abdominal pain. Serum alkaline phosphatase and cholesterol rise, but aminotransferases are only modestly elevated. Ultrasound and cholangiography are normal. The evaluation of the pregnant woman with cholestasis involves excluding other causes of jaundice and pruritus including viral hepatitis, primary biliary cirrhosis and biliary tract disease by acute fatty liver of pregnancy the appropriate laboratory and ultrasound investigations. Liver biopsy, which shows only cholestasis without inflammation, may be necessary in some atypical cases.
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